The study aimed at examining the relationship between role conflict and affective commitment of academics after the second educational reform in Thailand and tested the mediating effect of job satisfaction in the relationship. Data were obtained from 195 academics working in public and private universities located in Bangkok, using a self-administered questionaire. Results of regression analyses indicated that role conflict was directly and negatively related to affective commitment. It was also found that job satisfaction mediated the influence of role conflict on affective commitment. Implications of findings, limitations, and directions for future research are discussed.