Determine marketing strategies for innovative product especially for non-existing demand in market is considered as challenge. This research is funded by Thailand Research Fund (TRF) aiming to explore commercial marketing opportunity, marketing mix, and marketing strategies with collecting both qualitative and quantitative data regarding to the study of “Anti-Colon Cancer Supplementary Food Extracted from Dry Logan” as a case study. The results show that this innovative substance significantly creates a potential marketing opportunity once it is presented in form of supplements. However it is crucial to educate target consumer of functional benefit prevent by study and determine as well as position the product in order that target consumer can get to know the difference between benefit of fresh Longan and supplements from dried Longan extract. This is due to low awareness toward this substance (Polyphenol) among consumers.