The objective of this research were: 1) to study the attitude of Myanma labor in Samut-Prakarn Province towards quality of life in 7 dimensions, which include human physical, mindset, family, workplace, economy, social, and environment. 2) to study the requirement of quality of life improvement. 3) to compare the attitude of Myanma labor towards quality of life. This research had been executed by studying in both quantitative and qualitative approaches. There were 2 groups of population which were 1) the group of Myanma labor and 2) the group of Public officer and Thai people who lived in Samut-Prakarn Province. In gathering data, 400 number of sample from Group1 had been collected data by designed questionnaire for approach and other 13 number of sample had been interviewed and focus group executed for qualitative approach. Not only that, 5 key informants from group 2 had been interviewed for qualitative approach. Then, the data were analyzed by descriptive and inferential statistic for quantitative method and content analyzing for qualitative method. The research found that 1) the sample group had attitude towards quality of life at level medium for almost all dimensions, which include human physical, mindset, family, workplace, social, and environment, but the attitude in economic dimension was found at low level. 2) the dimension of quality of life that most required to be developed was economy then, follow with the dimensions of family, working, social, human physical and mindset, respectively. 3) Comparing the different of attitude of the sample group towards quality of life, this research found that the sample group with different gender, income, occupation, marital status, period of working in Thailand, and the condition of with/ without work permit had different attitude towards the quality of life, significantly. Meanwhile, the sample group with different age had no different attitude towards quality of life. The recommendations from this research had provided that the employer should fairly hire the employees and conformed with the law, and the public sector should monitor the consumer goods to not over price. Considering the quality of life in economic dimension that was evaluated by the sample group to be in the lowest level and therefore, needed to be develop most, had involved with the factors of working in Thailand period and the Kingdom with a work permit. The public sector should take care and issue work permit with more convenience and faster.